Description

Capsular Polysaccharide K49 is a high-purity, structurally defined bacterial polysaccharide antigen. This compound is critical for the research and development of advanced vaccines and immunological diagnostics, offering a precise and reliable target for antibody production and immune response studies. It is primarily utilized by biotechnology and pharmaceutical companies engaged in vaccine development, immunological research, and the production of diagnostic reagents.

Application

• Conjugate Vaccine Development: Serves as a key antigenic component for the formulation of glycoconjugate vaccines targeting specific bacterial pathogens.
• Immunological Research: Used as a standard or immunogen in studies of host-pathogen interactions, immune response mechanisms, and serotype characterization.
• Diagnostic Reagent Production: Essential for manufacturing ELISA kits, latex agglutination tests, and other immunoassays for the detection of specific bacterial antibodies.
• Quality Control Reference Standard: Acts as a reference material for the quality assurance and lot-to-lot consistency testing of vaccine products and diagnostic tools.
• Antibody Production & Purification: Employed to generate and affinity-purify monoclonal or polyclonal antibodies with high specificity for the K49 serotype.
• Biomaterial & Adjuvant Studies: Investigated for its potential role in novel drug delivery systems or as an immune-stimulating component in adjuvant formulations.

Basic Information

Product Name	Capsular Polysaccharide K49
CAS No.	130787-82-5
Molecular Formula	Contact for details
Molecular Weight	High Molecular Weight Polymer
Synonyms	K49 Capsular Polysaccharide
K49 Antigen
Poly-K49
Bacterial Capsular Polysaccharide Serotype K49
K49 CPS
K49 Polysaccharide Antigen
K49 Serotype Polysaccharide
EINECS	Contact for details

Quality Control

Our Capsular Polysaccharide K49 is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the rigorous standards required for immunological applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as polysaccharide content, molecular size distribution, and purity from protein and nucleic acid contaminants.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR/NMR)	Conforms to reference spectrum
Polysaccharide Content (Colorimetric)	≥ 90%
Protein Content (Lowry/Bradford)	≤ 1.0%
Nucleic Acid Content (UV)	≤ 2.0%
Moisture Content (KF)	≤ 5.0%
Molecular Size Distribution (SEC-HPLC)	Reported on COA
Endotoxin (LAL)	< 10 EU/mg
Sterility (Membrane Filtration)	Sterile or Low Bioburden (as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.