Description

trans-7,8-Dihydroxy-7,8-Dihydroquinoline CAS NO 130536-40-2 is a high-purity, specialized dihydroquinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique fused-ring structure with vicinal diol functionality makes it a valuable precursor for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological or anti-infective pathways.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its quinoline core for bioactive molecule design.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chelating ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the multistep synthesis of dyes, pigments, and other high-value specialty chemicals.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic synthesis, including oxidation, reduction, and cyclization reactions.
• Material Science Research: Investigated as a monomer or functional additive for developing advanced polymeric materials with specific optical or electronic properties.

Basic Information

Product Name	trans-7,8-Dihydroxy-7,8-Dihydroquinoline
CAS No.	130536-40-2
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	trans-7,8-Dihydroxy-5,6,7,8-tetrahydroquinoline; (7R,8R)-7,8-Dihydroxy-7,8-dihydroquinoline; (7S,8S)-7,8-Dihydroxy-7,8-dihydroquinoline; 7,8-Dihydroxy-5,6,7,8-tetrahydroquinoline; Quinoline-7,8-diol, 5,6,7,8-tetrahydro-; 5,6,7,8-Tetrahydroquinoline-7,8-diol; 7,8-Dihydroxy-1-azanaphthalene, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Every batch of trans-7,8-Dihydroxy-7,8-Dihydroquinoline is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and industrial-scale customers. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.