Description

(+-)-trans-5,6-Dihydroxy-5,6-Dihydroquinoline CAS NO 130536-38-8 is a high-purity, synthetic dihydroxyquinoline derivative that serves as a versatile and critical chiral building block in advanced organic synthesis. Its unique fused-ring structure with adjacent hydroxyl groups makes it a valuable precursor for developing complex molecules with specific stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), fine chemicals, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Ligand Synthesis: Used to construct sophisticated chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Fine Chemical Production: Serves as a building block for synthesizing complex, high-value specialty chemicals used in agrochemicals and advanced materials.
• Biochemical Research: Employed as a standard or reagent in studies involving quinoline-based natural products and their biological pathways.
• Academic & Industrial R&D: Essential for methodological development in organic chemistry, enabling new routes to stereochemically defined heterocyclic compounds.

Basic Information

Product Name	(+-)-trans-5,6-Dihydroxy-5,6-Dihydroquinoline
CAS No.	130536-38-8
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	(±)-trans-5,6-Dihydroxy-5,6-dihydroquinoline; 5,6-Dihydroxy-5,6-dihydroquinoline (racemic trans isomer); trans-5,6-Dihydroxy-1,2,3,4-tetrahydroquinoline; 5,6-Dihydroxy-1,2,3,4-tetrahydroquinoline; Quinoline-5,6-diol, 5,6-dihydro-; 5,6-Dihydroquinoline-5,6-diol; DL-trans-5,6-Dihydroxy-5,6-dihydroquinoline
EINECS	Contact for details

Quality Control

Every batch of (+-)-trans-5,6-Dihydroxy-5,6-Dihydroquinoline is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral composition is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99:1 trans/cis ratio
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.