Description

1,4-Benzodioxin-6-Methanamine, 2,3-Dihydro-N,n-Dimethyl-α-(Phenylm Ethyl)-, Hydrochloride is a specialized organic salt of significant interest in advanced chemical synthesis. This compound matters as a high-purity, structurally complex intermediate, enabling the development of novel molecules with targeted properties. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities for biological evaluation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) or receptor-targeted therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore novel chemical space and improve drug candidate profiles.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing reaction conditions for the production of candidate drugs during preclinical and clinical stages.
• Reference Standard: Acts as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement in vitro and in vivo.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client-specific research programs.

Basic Information

Product Name	1,4-Benzodioxin-6-Methanamine, 2,3-Dihydro-N,n-Dimethyl-α-(Phenylm Ethyl)-, Hydrochloride
CAS No.	130397-02-3
Molecular Formula	C20H24ClNO2
Molecular Weight	345.86 g/mol
Synonyms	N,N-Dimethyl-1-(1,4-benzodioxan-6-yl)-2-phenylethylamine hydrochloride; 6-[2-(Dimethylamino)-1-phenylethyl]-1,4-benzodioxane hydrochloride; 1-(1,4-Benzodioxan-6-yl)-N,N-dimethyl-2-phenylethylamine HCl; 2,3-Dihydro-N,N-dimethyl-α-(phenylmethyl)-1,4-benzodioxin-6-methanamine hydrochloride; L-687,384 hydrochloride; (R*,S*)-(±)-6-[2-(Dimethylamino)-1-phenylethyl]-1,4-benzodioxane hydrochloride
EINECS	Contact for details

Quality Control

Our 1,4-Benzodioxin-6-Methanamine, 2,3-Dihydro-N,n-Dimethyl-α-(Phenylm Ethyl)-, Hydrochloride is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.