Description

()-11-Nor-9-Carboxy-δ9-THC-d3 (Solution) is a high-purity, deuterium-labeled internal standard solution, essential for precise quantitative analysis in mass spectrometry. This certified reference material is critical for ensuring analytical accuracy, method validation, and regulatory compliance in forensic and clinical testing. It is primarily required by analytical laboratories, forensic science institutions, and pharmaceutical R&D departments engaged in cannabinoid metabolite research and toxicology studies.

Application

• Quantitative Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the accurate quantification of the primary THC metabolite, 11-nor-9-carboxy-δ9-THC, in biological matrices such as urine, blood, and oral fluid.
• Forensic Toxicology & Workplace Drug Testing: Essential for calibrating instruments and validating methods in forensic laboratories and drug testing facilities to ensure legally defensible results.
• Clinical Research & Pharmacokinetic Studies: Enables precise measurement of THC metabolite levels in human studies investigating cannabis use, metabolism, and elimination.
• Method Development & Validation: Serves as a critical component in developing and validating new analytical methods for cannabinoid detection, improving accuracy and reducing matrix effects.
• Quality Control & Proficiency Testing: Employed in the preparation of quality control samples and proficiency testing schemes for laboratory accreditation programs.
• Reference Material for Certified Standards: Acts as a primary reference material for the preparation and certification of secondary calibration standards.

Basic Information

Item	Detail
Product Name	()-11-Nor-9-Carboxy-δ9-THC-d3 (Solution)
CAS No.	130381-15-6
Molecular Formula	C₂₁H₂₇DO₄
Molecular Weight	344.45 g/mol (for monoisotopic mass)
Synonyms	11-Nor-9-carboxy-δ9-tetrahydrocannabinol-d3; 11-Nor-δ9-THC-9-COOH-d3; THC-COOH-d3; 11-Nor-9-Carboxy-δ9-THC Deuterated; δ9-THC-11-oic Acid-d3; 1,1,1-trideuterio-6-hydroxy-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-carboxylic acid; Deuterated THC Metabolite; THC Metabolite-d3 Internal Standard
EINECS	Contact for details

Quality Control

Every batch of ()-11-Nor-9-Carboxy-δ9-THC-d3 (Solution) is manufactured and analyzed under strict quality systems. We provide comprehensive Certificates of Analysis (COA) that include data for identity, purity (assay), chemical and isotopic purity, concentration, and solvent verification. Our quality commitment ensures the material meets the stringent requirements for forensic and clinical reference standards, supporting laboratories in achieving ISO/IEC 17025 accreditation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C ± 5°C. The solution is provided in a suitable organic solvent; handle with appropriate precautions in a well-ventilated area. Allow the vial to equilibrate to room temperature before use to ensure accurate volumetric dispensing.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (NMR & MS)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Isotopic Purity (deuterium)	≥98.0 atom % D
Chemical Purity (HPLC)	≥99.0%
Concentration	100 µg/mL ± 5% (or as specified)
Solvent	Methanol, Acetonitrile, or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.