Description

3-Amino-Cyclobutanemethanol Hydrochloride is a high-purity, functionalized cyclobutane derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, four-membered ring scaffold with both amino and hydroxymethyl functional groups, enabling the construction of complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, including protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can impart unique biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The structural motif is valuable for designing and synthesizing peptide analogs and conformationally restricted peptidomimetics.
• Material Science Precursor: Potential use in synthesizing specialized monomers for high-performance polymers and advanced materials.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and exploring new synthetic routes.

Basic Information

Item	Details
Product Name	3-Amino-Cyclobutanemethanol Hydrochloride
CAS No.	130369-06-1
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(3-Aminocyclobutyl)methanol hydrochloride; 3-(Hydroxymethyl)cyclobutanamine hydrochloride; 1-Amino-3-(hydroxymethyl)cyclobutane hydrochloride; 3-Aminocyclobutanemethanol HCl; Aminocyclobutanemethanol hydrochloride; Cyclobutanemethanol, 3-amino-, hydrochloride; (3-Aminocyclobutyl)methanol HCl
EINECS	Contact for details

Quality Control

Our 3-Amino-Cyclobutanemethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.