Description

S-(+)-tert-Butyl Glycidyl Ether is a high-value, chiral glycidyl ether derivative, prized for its role as a versatile chiral building block in asymmetric synthesis. Its enantiomeric purity makes it a critical intermediate for introducing the tert-butoxy moiety with defined stereochemistry into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalyst and Ligand Preparation: Used in the synthesis of chiral ligands and organocatalysts for stereoselective transformations.
• Agrochemical Active Ingredient Development: Serves as a chiral synthon for creating herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Advanced Material Monomer: Employed in the synthesis of specialty polymers and resins where the chiral center imparts specific optical or mechanical properties.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex natural products and novel chemical entities.

Basic Information

Product Name	S-(+)-tert-Butyl Glycidyl Ether
CAS No.	130232-97-2
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(S)-(+)-tert-Butyl Glycidyl Ether; (S)-tert-Butyloxirane; (S)-2-(tert-Butoxymethyl)oxirane; (+)-tert-Butyl Glycidyl Ether; (S)-Glycidyl tert-Butyl Ether; (S)-1-tert-Butoxy-2,3-epoxypropane; (S)-TBGE; (2S)-2-[(2-Methylpropan-2-yl)oxymethyl]oxirane
EINECS	Contact for details

Quality Control

Our S-(+)-tert-Butyl Glycidyl Ether is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, purity, and optical rotation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Optical Rotation [α]	+10.0° to +12.0° (c=1, CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.