Description

4,5-Difluoro-2-Iodobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile synthetic building block for constructing complex organic molecules. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination and iodination patterns are required for modulating biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, where the difluoro and iodo substituents enhance bioavailability and target binding.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated organic electronic materials for displays and lighting applications.
• Cross-Coupling Reactions: Serves as a valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, process chemistry, and exploring new synthetic methodologies in academic and industrial R&D labs.
• Positron Emission Tomography (PET) Tracer Development: Potential precursor for synthesizing fluorine-18 labeled radiopharmaceuticals for diagnostic imaging.

Basic Information

Product Name	4,5-Difluoro-2-Iodobenzoic Acid
CAS No.	130137-05-2
Molecular Formula	C7H3F2IO2
Molecular Weight	283.99 g/mol
Synonyms	2-Iodo-4,5-difluorobenzoic Acid; Benzoic acid, 4,5-difluoro-2-iodo-; 4,5-Difluoro-2-iodobenzoic acid; 130137-05-2; 2-Iodo-4,5-difluorobenzoic acid; 4,5-Difluoro-o-iodobenzoic acid
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global customer base in advanced synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.