Description

6-Fluoro-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid is a high-purity fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in the synthesis of antibacterial and anticancer agents. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluoroquinolone antibiotics and other bioactive molecules targeting bacterial DNA gyrase and topoisomerase IV.
• Anticancer Drug Research: Used in the research and development of novel chemotherapeutic agents due to the quinoline scaffold's biological activity.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and pesticides with enhanced efficacy.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for complex, fluorinated organic molecules.
• Biochemical Research: Used as a reference standard or probe in biochemical studies to investigate enzyme inhibition and mechanism of action.
• Material Science Precursor: Potential intermediate for the synthesis of organic ligands used in catalytic systems or advanced materials.

Basic Information

Product Name	6-Fluoro-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid
CAS No.	130064-10-7
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	6-Fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid; 6-Fluoro-1,4-dihydro-4-oxoquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 1,4-dihydro-6-fluoro-4-oxo-; 6-Fluoro-4-oxo-1H-quinoline-2-carboxylic acid; 6-Fluoro-4-oxoquinoline-2-carboxylic acid; 6-Fluoro-2-carboxy-4-quinolone; 6-Fluoro-4-hydroxyquinoline-2-carboxylic acid (tautomer)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.