Description

Dibenzo(A,L)Pyrene 8,9-Dihydrodiol is a high-purity, advanced polycyclic aromatic hydrocarbon (PAH) metabolite of significant interest in toxicological and environmental research. This compound serves as a critical reference standard and biochemical tool for studying metabolic activation pathways, DNA adduct formation, and the carcinogenic mechanisms of complex PAHs. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in cancer research, environmental monitoring, and chemical safety assessment.

Application

• Analytical Reference Standard: For use in high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS) for the quantification and identification of PAH metabolites in complex matrices.
• Biochemical Research: As a substrate or intermediate in enzymatic studies to investigate the metabolic pathways of dibenzo(a,l)pyrene, a potent carcinogen.
• Toxicology Studies: For in vitro and in vivo research on the genotoxicity, mutagenicity, and carcinogenicity of polycyclic aromatic hydrocarbons.
• Environmental Science: As a biomarker in studies assessing human and ecological exposure to PAH contamination from sources like air pollution, cigarette smoke, and cooked foods.
• DNA Adduct Research: Used to synthesize and study specific DNA adducts to understand the molecular basis of PAH-induced carcinogenesis.
• Quality Control & Method Development: For calibrating instruments and validating analytical methods in compliance with environmental and occupational health regulations.

Basic Information

Product Name	Dibenzo(A,L)Pyrene 8,9-Dihydrodiol
CAS No.	130063-43-3
Molecular Formula	C24H16O2
Molecular Weight	336.38 g/mol
Synonyms	DBalP 8,9-dihydrodiol; Dibenzo[a,l]pyrene-8,9-dihydrodiol; 8,9-Dihydroxy-8,9-dihydrodibenzo[a,l]pyrene; (+/-)-Dibenzo(a,l)pyrene-8,9-diol; 8,9-Dihydrodibenzo[a,l]pyrene-8,9-diol; Dibenzo(def,p)chrysene-8,9-dihydrodiol; 8,9-Dihydroxy-8,9-dihydrodibenzo(def,p)chrysene
EINECS	Contact for details

Quality Control

Every batch of Dibenzo(A,L)Pyrene 8,9-Dihydrodiol is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed results for purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.