Description

5-Amino-2-Fluorobenzoic Acid Hydrochloride is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a fluorine atom on the aromatic ring, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated aniline-benzoic acid motifs.

Basic Information

Product Name	5-Amino-2-Fluorobenzoic Acid Hydrochloride
CAS No.	130047-15-3
Molecular Formula	C7H7FNO2 • HCl
Molecular Weight	191.59 (Free base) / 228.05 (HCl salt)
Synonyms	2-Fluoro-5-aminobenzoic Acid Hydrochloride; Benzoic acid, 5-amino-2-fluoro-, hydrochloride; 5-Amino-2-fluorobenzoic acid HCl; 2-Fluoro-5-nitrobenzoic Acid (precursor); 5-Amino-2-fluorobenzoate hydrochloride; 130047-15-3; 5-Amino-2-fluoro-benzoic acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluorobenzoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.