Description

4-Aminophenyl-β-D-Thiomannopyranoside is a specialized thioglycoside derivative of mannose, featuring an aminophenyl aglycone. This compound is a critical building block and biochemical tool, valued for its role in synthesizing glycoconjugates and enzyme substrates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in glycobiology, drug discovery, and the development of enzyme inhibitors.

Application

• Glycobiology Research: Serves as a key intermediate for the synthesis of complex oligosaccharides and glycoconjugates to study carbohydrate-protein interactions.
• Enzyme Substrate Development: Used in the design and synthesis of substrates for glycosidase and glycosyltransferase enzymes to study enzyme mechanisms and inhibition.
• Pharmaceutical Intermediates: Acts as a crucial precursor in the development of novel therapeutic agents, including antiviral and anticancer drugs that target carbohydrate-mediated processes.
• Diagnostic Reagent Synthesis: Employed in the production of labeled probes and reagents for diagnostic assays and imaging techniques.
• Bioconjugation Chemistry: The aminophenyl group facilitates conjugation to proteins, peptides, or surfaces for creating targeted bioprobes and biomaterials.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other chemical proteomics strategies to identify and characterize glycosidases.

Basic Information

Product Name	4-Aminophenyl-β-D-Thiomannopyranoside
CAS No.	129970-93-0
Molecular Formula	C12H17NO5S
Molecular Weight	287.33 g/mol
Synonyms	4-Aminophenyl 1-Thio-β-D-mannopyranoside; p-Aminophenyl β-D-Thiomannopyranoside; 1-Thio-β-D-mannopyranoside, 4-aminophenyl; APTM; 4-Aminophenyl β-D-mannothiopyranoside; 4-AP-β-D-thiomannoside; 4-Aminophenyl 1-deoxy-1-thio-β-D-mannopyranoside
EINECS	Contact for details

Quality Control

Our 4-Aminophenyl-β-D-Thiomannopyranoside is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.