Description

6-Bromo-8-(Chloromethyl)-4H-1,3-Benzodioxine is a high-purity, multi-functional chemical intermediate characterized by its halogenated benzodioxine structure. This compound is valued for its reactivity, particularly at the chloromethyl and bromo substituents, making it a versatile building block for advanced synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antimicrobial drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for developing specialty polymers, ligands, and functional organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	6-Bromo-8-(Chloromethyl)-4H-1,3-Benzodioxine
CAS No.	129888-79-5
Molecular Formula	C9H8BrClO2
Molecular Weight	263.52 g/mol
Synonyms	6-Bromo-8-(chloromethyl)-4H-benzo[d][1,3]dioxine; 4H-1,3-Benzodioxine, 6-bromo-8-(chloromethyl)-; 8-Chloromethyl-6-bromo-4H-1,3-benzodioxine; 6-Bromo-8-chloromethyl-1,3-benzodioxin; 129888-79-5; Benzodioxine, 6-bromo-8-(chloromethyl)-4H-
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-(Chloromethyl)-4H-1,3-Benzodioxine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.