Description

7-Bromo-1,4,4-Trimethyl-3,4-Dihydro-1H-Quinolin-2-One is a high-value brominated quinolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it an essential building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the quinolinone scaffold for biological activity.
• Material Science: Serves as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other advanced functional materials due to its conjugated system and bromine handle for further cross-coupling reactions.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to introduce complex quinolinone motifs into larger molecular architectures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	7-Bromo-1,4,4-Trimethyl-3,4-Dihydro-1H-Quinolin-2-One
CAS No.	129790-06-3
Molecular Formula	C₁₂H₁₄BrNO
Molecular Weight	268.15 g/mol
Synonyms	7-Bromo-1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one; 7-Bromo-1,4,4-trimethyl-1,4-dihydroquinolin-2-one; 1,4,4-Trimethyl-7-bromo-3,4-dihydro-1H-quinolin-2-one; 7-Bromo-1,4,4-trimethyl-2-oxo-1,2,3,4-tetrahydroquinoline; 129790-06-3; Quinolin-2-one, 7-bromo-1,4,4-trimethyl-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.