Description

5-Hydroxy-8-Nitroquinoline is a versatile nitro-substituted quinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique structure, combining a hydroxyl group with a nitro moiety on the quinoline scaffold, makes it valuable for constructing complex molecules with specific electronic and binding properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides that leverage the bioactive quinoline core.
• Coordination Chemistry & Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis, metal extraction, and sensor technology.
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its electron-accepting nitro group.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized nitroquinoline-derived dyes and colorants.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	5-Hydroxy-8-Nitroquinoline
CAS No.	129717-35-7
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	8-Nitro-5-quinolinol; 5-Hydroxy-8-nitroquinoline; 8-Nitro-5-hydroxyquinoline; 5-Quinolinol, 8-nitro-; Quinolin-5-ol, 8-nitro-; 129717-35-7; 5-Hydroxy-8-nitro-quinoline
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-8-Nitroquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.