Description

3-Sulfoglucuronyl-Lactosaminyl-Paragloboside is a complex, sulfated glycosphingolipid (sulfatide) that serves as a critical intermediate in the biosynthesis of specific gangliosides and other bioactive glycoconjugates. This compound is of significant value in biochemical research for studying cell surface recognition, signal transduction, and the molecular mechanisms underlying various biological processes. It is primarily utilized by researchers and developers in the fields of glycobiology, neuroscience, immunology, and diagnostic reagent development, where precise carbohydrate structures are essential for functional studies and assay development.

Application

• Biochemical Research: As a standard or substrate for studying glycosyltransferase and sulfotransferase enzyme activities in glycolipid biosynthesis pathways.
• Neuroscience Studies: Investigation of its role in neural development, cell adhesion, and as a potential marker or ligand in neurological systems.
• Immunology & Cancer Research: Exploration of its function in cell-cell interactions, immune modulation, and its expression patterns in certain tumor cells.
• Diagnostic Development: Potential use as a reference compound or coating antigen in the development of immunoassays and biosensors targeting specific glycolipid antigens.
• Glycoconjugate Synthesis: Serving as a key building block or precursor for the chemical or enzymatic synthesis of more complex gangliosides and glycoconjugates.
• Membrane Biophysics: Study of its incorporation into lipid bilayers or liposomes to model membrane properties and carbohydrate-mediated interactions.

Basic Information

Product Name	3-Sulfoglucuronyl-Lactosaminyl-Paragloboside
CAS No.	129429-42-1
Molecular Formula	C55H94N2O33S
Molecular Weight	1343.39 g/mol
Synonyms	SGPG (3'-Sulfoglucuronyl Paragloboside); 3'-Sulfoglucuronylneolactotetraosylceramide; 3-SO3-GlcA-β1-3Gal-β1-4GlcNAc-β1-3Gal-β1-4Glc-β1-1'Cer; Sulfated Glucuronyl Paragloboside; HNK-1 Carbohydrate Epitope; Human Natural Killer-1 Epitope; L2/HNK-1 Glycan; CD57 Antigen (carbohydrate epitope)
EINECS	Contact for details

Quality Control

Our 3-Sulfoglucuronyl-Lactosaminyl-Paragloboside is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, MS, and NMR, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere or desiccated conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in Chloroform/Methanol/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.