Description

Acetophenone, 4-(2-(4-Methyl-1-piperazinyl)-4-quinazolinyloxy)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel quinazoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The quinazoline-piperazine core is a privileged structure in the design of potential tyrosine kinase inhibitors for oncology research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for biological evaluation.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Acetophenone, 4-(2-(4-Methyl-1-piperazinyl)-4-quinazolinyloxy)-
CAS No.	129112-42-1
Molecular Formula	C21H22N4O2
Molecular Weight	362.43 g/mol
Synonyms	4-(2-(4-Methylpiperazin-1-yl)quinazolin-4-yloxy)acetophenone; 1-[4-[2-(4-Methyl-1-piperazinyl)-4-quinazolinyl]oxy]phenyl]ethanone; 4-(2-(4-Methyl-1-piperazinyl)-4-quinazolinyloxy)acetophenone; CAS 129112-42-1; AQMP; 4-Quinazolinol, 2-(4-methyl-1-piperazinyl)-, 4-(4-acetylphenyl) ether
EINECS	Contact for details

Quality Control

Our Acetophenone, 4-(2-(4-Methyl-1-piperazinyl)-4-quinazolinyloxy)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.