Description

Repinotan is a high-purity, non-peptide aminotetralin derivative with potent and selective 5-HT1A receptor agonist activity. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its neuroprotective potential. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics for central nervous system disorders, including stroke and neuropathic pain.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting serotonin receptors.
• Neurological Research: Used as a reference standard and experimental compound in preclinical studies investigating neuroprotection, ischemia, and stroke recovery mechanisms.
• Receptor Binding Assays: Employed in vitro to study the binding affinity and functional activity at 5-HT1A receptor sites.
• Drug Discovery Programs: A key candidate in medicinal chemistry programs aimed at developing new anxiolytic and antidepressant agents.
• Biochemical Tool Compound: Utilized in laboratory settings to elucidate serotoninergic pathways and their role in various physiological and pathological processes.

Basic Information

Product Name	Repinotan
CAS No.	129091-16-3
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	BAY x 3702; Repinotan hydrochloride; (R)-(-)-2-[4-[(Chroman-2-ylmethyl)amino]butyl]-1,2-benzisothiazol-3(2H)-one 1,1-dioxide; BAY-3702; UNII-6B5K5Q8H3I
EINECS	Contact for details

Quality Control

Our Repinotan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.