Description

1-Propanone, 2-Chloro-1-Tricyclo[3.2.1.02,4]Oct-3-Yl-, [3(S)-(1Alpha,2Beta,3Alpha,4Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chlorinated ketone derivative of a tricyclooctane scaffold. This compound matters as a sophisticated chiral building block and intermediate, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers focused on advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or other targeted therapies.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Material Science: Acts as a precursor for synthesizing specialty polymers, resins, or liquid crystals where the rigid tricyclic structure imparts unique physical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for methodological studies, asymmetric synthesis, and the development of new catalytic transformations.
• Flavor & Fragrance Chemistry: Potential use as an intermediate for creating complex, high-value aroma chemicals with unique olfactory profiles.

Basic Information

Item	Details
Product Name	1-Propanone, 2-Chloro-1-Tricyclo[3.2.1.02,4]Oct-3-Yl-, [3(S)-(1Alpha,2Beta,3Alpha,4Beta,5Alpha)]- (9Ci)
CAS No.	128949-46-2
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	2-Chloro-1-(tricyclo[3.2.1.0²,⁴]oct-3-yl)propan-1-one; (1S,2R,3S,4S,5R)-2-Chloro-1-(tricyclo[3.2.1.0²,⁴]oct-3-yl)propan-1-one; 2-Chloro-1-tricyclo[3.2.1.0²,⁴]oct-3-ylpropan-1-one; Chiral Tricyclooctyl Chloroketone; (3S)-(1α,2β,3α,4β,5α)-2-Chloro-1-tricyclo[3.2.1.0²,⁴]oct-3-yl-1-propanone
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Chloro-1-Tricyclo[3.2.1.02,4]Oct-3-Yl-, [3(S)-(1Alpha,2Beta,3Alpha,4Beta,5Alpha)]- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, strength, and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.