Description

(1R 5S)-3-Oxabicyclo(3.3.0)Oct-6-En-2-On is a high-purity chiral bicyclic lactone, a key synthetic intermediate in advanced organic chemistry. Its rigid, oxygen-containing fused ring structure makes it a valuable building block for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other complex therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis: Serves as a precursor or ligand framework in the development of chiral catalysts for enantioselective reactions.
• Fine Chemical Production: A building block for fragrances, flavors, and other high-value specialty chemicals requiring defined stereocenters.
• Academic & R&D: Employed in organic synthesis research for methodology development and the construction of natural product analogs.
• Material Science: Potential monomer for creating novel polymers with specific thermal or mechanical properties derived from its bicyclic structure.

Basic Information

Product Name	(1R 5S)-3-Oxabicyclo(3.3.0)Oct-6-En-2-On
CAS No.	128946-78-1
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	(1R,5S)-3-Oxabicyclo[3.3.0]oct-6-en-2-one; (1R,5S)-6,8-Dioxabicyclo[3.3.0]oct-3-ene; (-)-(1R,5S)-3-Oxabicyclo[3.3.0]oct-6-en-2-one; Bicyclic Lactone Intermediate; Chiral Oxabicycloactone
EINECS	Contact for details

Quality Control

Every batch of (1R 5S)-3-Oxabicyclo(3.3.0)Oct-6-En-2-On is produced and tested under a strict quality management system. We guarantee high chiral purity and chemical integrity through advanced analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.