Description

1-(Benzyloxy)-3-Bromo-5-Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, offering reactive handles for bromination and nitration chemistry, which is critical for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated and nitrated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo and nitro functional groups are essential for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex nitro- and bromo-substituted dyes and organic pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the presence of the bromine atom.

Basic Information

Product Name	1-(Benzyloxy)-3-Bromo-5-Nitrobenzene
CAS No.	128923-99-9
Molecular Formula	C₁₃H₁₀BrNO₃
Molecular Weight	308.13 g/mol
Synonyms	3-Bromo-5-nitrobenzyl phenyl ether; 3-Bromo-5-nitro-1-(phenylmethoxy)benzene; Benzene, 1-(benzyloxy)-3-bromo-5-nitro-; 1-Benzyloxy-3-bromo-5-nitrobenzene; 3-Bromo-5-nitro diphenyl ether; (3-Bromo-5-nitrophenyl)(phenyl)methanol (tautomer check); BBNB (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 1-(Benzyloxy)-3-Bromo-5-Nitrobenzene is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.