Description

7-(2-Aminoethylthio)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, offering a strategic pathway for drug development. It is essential for R&D laboratories, fine chemical manufacturers, and pharmaceutical companies focused on developing next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced fluoroquinolone antibiotic candidates.
• Antibacterial Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new antibacterial agents.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic molecules in organic synthesis.
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs) targeting bacterial infections.
• Biochemical Research: Used as a tool compound to study bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.

Basic Information

Product Name	7-(2-Aminoethylthio)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	128751-33-7
Molecular Formula	C15H15FN2O3S
Molecular Weight	322.36 g/mol
Synonyms	1-Cyclopropyl-7-[(2-aminoethyl)thio]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 7-(2-Aminoethylthio)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[(2-aminoethyl)thio]-3-quinolinecarboxylic Acid; Fluoroquinolone Intermediate; Quinolone Carboxylic Acid Derivative; 128751-33-7; CAS 128751-33-7
EINECS	Contact for details

Quality Control

Our production of 7-(2-Aminoethylthio)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.