Description

7-(2-Aminoethoxy)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of modern fluoroquinolone antibiotics, offering a pathway to molecules with enhanced potency and spectrum of activity. It is essential for R&D laboratories and manufacturing facilities focused on developing and producing next-generation antibacterial agents.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: A vital precursor in the synthesis of novel antibacterial agents targeting resistant pathogens.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final or penultimate steps of manufacturing complex antibiotic APIs under GMP conditions.
• Biochemical Research: Utilized as a tool compound to study bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	7-(2-Aminoethoxy)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	128751-31-5
Molecular Formula	C15H15FN2O4
Molecular Weight	306.29 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(2-aminoethoxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-(2-Aminoethoxy)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(2-aminoethoxy)-3-quinolinecarboxylic acid; Ciprofloxacin EP Impurity F; Ciprofloxacin Intermediate; Ciprofloxacin Related Compound F; 7-(2-Aminoethoxy)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 7-(2-Aminoethoxy)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality systems to meet the rigorous demands of pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with relevant standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.