Description

2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid is a high-value, fluorinated pyrazole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a trifluoromethyl group, makes it an essential precursor for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced materials with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid
CAS No.	128694-63-3
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	2-Methyl-5-(trifluoromethyl)-2H-pyrazole-3-carboxylic acid; 3-Carboxy-2-methyl-5-trifluoromethylpyrazole; 5-(Trifluoromethyl)-2-methyl-2H-pyrazole-3-carboxylic acid; 2-Methyl-5-trifluoromethylpyrazole-3-carboxylic acid; MTFPC Acid; 2-Methyl-5-trifluoromethyl-1H-pyrazole-3-carboxylic acid (tautomer form)
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-Trifluoromethyl-2H-Pyrazole-3-Carboxylic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.