Description

6-Hydroxy-1-Iodonaphthalene is a high-purity iodinated naphthalene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive iodine atom and a phenolic hydroxyl group, makes it indispensable for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing naphthalene cores or requiring halogenated aromatic intermediates for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that utilize halogenated aromatic compounds.
• Material Science: Serves as a monomer or building block for the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, enabling the formation of carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized to create sophisticated ligands for metal catalysts or as a scaffold for functional molecules in catalysis research.
• Dye and Pigment Intermediate: Acts as a starting material in the synthesis of specialized dyes, pigments, and fluorescent markers.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in university and industrial laboratories.

Basic Information

Product Name	6-Hydroxy-1-Iodonaphthalene
CAS No.	128542-54-1
Molecular Formula	C₁₀H₇IO
Molecular Weight	270.07 g/mol
Synonyms	1-Iodo-6-hydroxynaphthalene; 6-Hydroxynaphthalen-1-yl iodide; 6-Iodo-1-naphthol; 1-Naphthol, 6-iodo-; 6-Hydroxy-1-iodonaphthalene; Naphthalen-1-ol, 6-iodo-
EINECS	Contact for details

Quality Control

Every batch of 6-Hydroxy-1-Iodonaphthalene is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including HPLC, NMR, and FTIR analysis, to ensure compliance with industry standards and your specific research or production requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.