Description

1-Hydroxy-6-Iodonaphthalene is a halogenated naphthol derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a phenolic hydroxyl group and an iodine atom on the naphthalene ring system, makes it a critical building block for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments engaged in pharmaceutical development, materials science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs) due to its modifiable phenolic and halogen sites.
• Functional Material Development: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and sensors.
• Agrochemical Research: Intermediate in the development of novel crop protection agents and herbicides.
• Dye and Pigment Chemistry: Used in the synthesis of specialized iodinated dyes and colorants.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.

Basic Information

Item	Details
Product Name	1-Hydroxy-6-Iodonaphthalene
CAS No.	128542-53-0
Molecular Formula	C₁₀H₇IO
Molecular Weight	270.07 g/mol
Synonyms	6-Iodo-1-naphthol; 1-Naphthol, 6-iodo-; 6-Iodonaphthalen-1-ol; 1-Hydroxy-6-iodonaphthalene; 6-Iodo-1-hydroxynaphthalene; NSC 405124; AI3-52207
EINECS	Contact for details

Quality Control

Every batch of 1-Hydroxy-6-Iodonaphthalene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.