Description

Naphthalene, 2-Iodo-7-Methoxy- (9Ci) CAS NO 128542-48-3 is a halogenated, methoxy-substituted naphthalene derivative, serving as a valuable synthetic intermediate in advanced organic chemistry. This compound is particularly significant for its role in constructing complex molecular architectures, especially in pharmaceutical research and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use in cross-coupling reactions and as a building block for functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its rigid naphthalene core and functional groups.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Chemical Synthesis: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating complex heterocyclic compounds.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of specialized dyes and organic pigments.

Basic Information

Product Name	Naphthalene, 2-Iodo-7-Methoxy- (9Ci)
CAS No.	128542-48-3
Molecular Formula	C₁₁H₉IO
Molecular Weight	284.09 g/mol
Synonyms	2-Iodo-7-methoxynaphthalene; 7-Methoxy-2-iodonaphthalene; 2-Iodo-7-methoxy-naphthalene; 1-Iodo-6-methoxynaphthalene (registry number check advised); 128542-48-3; Naphthalene, 2-iodo-7-methoxy-; 2-Iodo-7-methoxynaphthalene (9CI)
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-7-methoxynaphthalene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request. Our quality protocols are designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.