Description

1-Tosyl-1,4,8,11-Tetraazacyclotetradecane Trihydrochloride is a high-purity, functionalized macrocyclic ligand derivative, essential for advanced coordination chemistry and catalysis research. Its core value lies in its ability to chelate metal ions with high selectivity, forming stable complexes for use in diagnostic imaging, targeted drug delivery, and material science. This compound is primarily needed by research institutions, pharmaceutical developers, and specialty chemical manufacturers working on contrast agents, radiopharmaceuticals, and novel catalytic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of macrocyclic chelators for gadolinium-based MRI contrast agents.
• Radiopharmaceutical Development: Used to create bifunctional chelators for labeling antibodies, peptides, and other targeting molecules with radioisotopes (e.g., 64Cu, 68Ga) for PET imaging and targeted radiotherapy.
• Catalysis Research: Serves as a ligand scaffold for designing transition metal catalysts used in organic synthesis and polymerization reactions.
• Chemical Sensing: Employed in the development of selective sensors and probes for metal ion detection in analytical and environmental chemistry.
• Material Science: Incorporated into functional materials, such as metal-organic frameworks (MOFs) or surface coatings, for specific adsorption or catalytic properties.
• Academic & Industrial R&D: A critical reagent for fundamental studies in coordination chemistry, supramolecular chemistry, and bioinorganic chemistry.

Basic Information

Product Name	1-Tosyl-1,4,8,11-Tetraazacyclotetradecane Trihydrochloride
CAS No.	128495-30-7
Molecular Formula	C19H35Cl3N4O2S
Molecular Weight	489.92 g/mol
Synonyms	1,4,8,11-Tetraazacyclotetradecane, 1-(4-methylbenzenesulfonyl)-, trihydrochloride; Cyclam Monotosylate Trihydrochloride; 1-Tosyl-1,4,8,11-tetraazacyclotetradecane HCl; TETRAHYDROCHLORIDE OF 1-TOSYL-1,4,8,11-TETRAAZACYCLOTETRADECANE; 1-Tosyl-1,4,8,11-tetraazacyclotetradecane hydrochloride (1:?); 1-(p-Toluenesulfonyl)-1,4,8,11-tetraazacyclotetradecane trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Tosyl-1,4,8,11-Tetraazacyclotetradecane Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.