Description

3-(Difluoromethyl)-4-Formyl-1-Methyl-1H-Pyrazole is a versatile and highly functionalized pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethyl and formyl groups, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated heterocycles to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and environmental profile.
• Material Science Research: Used in the development of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology & Medicinal Chemistry: Serves as a probe or scaffold in drug discovery programs for creating compound libraries and studying structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	3-(Difluoromethyl)-4-Formyl-1-Methyl-1H-Pyrazole
CAS No.	128225-66-1
Molecular Formula	C6H6F2N2O
Molecular Weight	160.12 g/mol
Synonyms	1-Methyl-3-(difluoromethyl)-1H-pyrazole-4-carboxaldehyde; 1-Methyl-3-(difluoromethyl)-4-formyl-1H-pyrazole; 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde; 4-Formyl-1-methyl-3-(difluoromethyl)pyrazole; 1H-Pyrazole-4-carboxaldehyde, 3-(difluoromethyl)-1-methyl-; DFMP
EINECS	Contact for details

Quality Control

Our production of 3-(Difluoromethyl)-4-Formyl-1-Methyl-1H-Pyrazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We operate under a quality system designed to meet the exacting standards of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.