Description

(1S,2R)-(+)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the (1S,2R) enantiomer of 2-aminocyclopentanecarboxylic acid. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly peptidomimetics and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries where precise stereochemistry and high purity are non-negotiable for efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, including protease inhibitors and other therapeutic peptides.
• Peptidomimetics Research: Used to construct conformationally constrained peptide analogs for structure-activity relationship (SAR) studies and drug discovery.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Biochemical Research: Employed in studies of enzyme mechanisms, metabolic pathways, and as a substrate analog.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals, advanced materials, and ligands for catalysis.
• Reference Standard: Qualified for use as a high-purity analytical reference standard in quality control laboratories.

Basic Information

Product Name	(1S,2R)-(+)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride
CAS No.	128052-92-6
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(1S,2R)-2-Aminocyclopentanecarboxylic Acid Hydrochloride; (1S,2R)-2-Amino-1-cyclopentanecarboxylic Acid HCl; cis-2-Aminocyclopentanecarboxylic Acid Hydrochloride (enantiomer); (1S,2R)-ACPC HCl; (1S,2R)-2-ACPC Hydrochloride; (1S,2R)-2-Amino-cyclopentane-1-carboxylic Acid Hydrochloride; (1S,2R)-2-Aminocyclopentane-1-carboxylic Acid Hydrochloride
EINECS	Contact for details

Quality Control

Our (1S,2R)-(+)-2-Amino-1-Cyclopentanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards for chiral purity, chemical purity, and identity. Certificates of Analysis (COA) detailing specific results for chiral HPLC assay, related substances, residual solvents, and other critical parameters are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.