Description

n-Methyl-3-Chloro-3-Phenyl Propylamine Hcl is a high-purity organic amine hydrochloride salt, serving as a critical chiral intermediate in advanced pharmaceutical synthesis. Its value lies in enabling the production of complex active pharmaceutical ingredients (APIs) with precise stereochemistry. This compound is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors, particularly those developing central nervous system (CNS) agents and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in neurological and psychiatric therapeutic areas.
• API Synthesis: Used in the production route of complex Active Pharmaceutical Ingredients (APIs) requiring specific stereochemical configurations.
• Asymmetric Synthesis: Employed in chiral pool synthesis and as a precursor for catalysts or ligands in asymmetric transformations.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Production: Utilized in the manufacture of other high-value, specialty organic compounds beyond pharmaceuticals.

Basic Information

Product Name	n-Methyl-3-Chloro-3-Phenyl Propylamine Hcl
CAS No.	128036-32-8
Molecular Formula	C10H14ClN•HCl
Molecular Weight	220.14 g/mol
Synonyms	1-(3-Chloro-3-phenylpropyl)-N-methylamine hydrochloride; (3-Chloro-3-phenylpropyl)methylamine hydrochloride; 3-Chloro-3-phenyl-N-methylpropan-1-amine hydrochloride; N-Methyl-3-chloro-3-phenylpropylamine hydrochloride; 3-Phenyl-3-chloro-N-methylpropylamine HCl; N-Methyl-3-chloro-3-phenyl-1-propanamine hydrochloride; 1-Amino-3-chloro-3-phenylpropane, N-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-3-Chloro-3-Phenyl Propylamine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including chiral purity assessment, to meet exacting customer requirements. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.