Description

6-Bromo-5-Fluoroquinoline Hydrochloride is a high-purity, halogenated quinoline derivative offered as a hydrochloride salt, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of both bromo and fluoro substituents onto the quinoline scaffold, which is pivotal for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting infectious diseases, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and insecticides where the quinoline core contributes to efficacy and environmental profile.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and fluorescent dyes or probes due to the quinoline structure's electronic properties.
• Chemical Biology: Serves as a precursor for designing molecular probes and enzyme inhibitors to study biological pathways and protein functions.
• Custom Synthesis & Scale-Up: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	6-Bromo-5-Fluoroquinoline Hydrochloride
CAS No.	127827-51-4
Molecular Formula	C9H6BrClFN
Molecular Weight	262.51 g/mol
Synonyms	5-Fluoro-6-bromoquinoline hydrochloride; 6-Bromo-5-fluoroquinoline HCl; Quinoline, 6-bromo-5-fluoro-, hydrochloride; 6-Bromo-5-fluoroquinoline monohydrochloride; 6-Br-5-F-quinoline HCl; 127827-51-4; 6-Bromo-5-fluoroquinoline hydrochloride salt
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and quality assurance requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.