Description

Methyl 2,4-Dioxo-1,2,3,4-Tetrahydro-5-Quinazolinecarboxylate is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a versatile quinazoline-dione scaffold for medicinal chemistry research and development. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex fused heterocyclic systems.
• Biochemical Tool Compound: Potential use in developing probes or inhibitors for biological assays and target validation.

Basic Information

Product Name	Methyl 2,4-Dioxo-1,2,3,4-Tetrahydro-5-Quinazolinecarboxylate
CAS No.	127801-84-7
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	5-Quinazolinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester; Methyl 1,2,3,4-tetrahydro-2,4-dioxo-5-quinazolinecarboxylate; 5-(Methoxycarbonyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione; 2,4-Dioxo-1,2,3,4-tetrahydroquinazoline-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,4-Dioxo-1,2,3,4-Tetrahydro-5-Quinazolinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.