Description

1-n-Boc-2-Methylhydrazine is a protected hydrazine derivative, a crucial building block in modern organic synthesis. Its primary value lies in its role as a versatile intermediate for introducing the methylhydrazine moiety into target molecules under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds. The CAS number for this material is 127799-54-6.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various drug candidates, including anticancer and antiviral agents.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and plant growth regulators requiring specific hydrazine-based structures.
• Peptide Chemistry: Serves as a reagent for the modification of peptides and the preparation of non-natural amino acid derivatives.
• Heterocyclic Compound Production: Integral in the construction of pyrazoles, pyrazolines, and other nitrogen-containing heterocycles.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties.
• Chemical Biology Probes: Utilized for labeling and cross-linking studies in proteomics and biochemical research.

Basic Information

Product Name	1-n-Boc-2-Methylhydrazine
CAS No.	127799-54-6
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	1-Boc-2-methylhydrazine; tert-Butyl 2-methylhydrazine-1-carboxylate; N-(tert-Butoxycarbonyl)-N'-methylhydrazine; 2-Methyl-1-(tert-butoxycarbonyl)hydrazine; Boc-NH-NH-CH3; N-Boc-N'-methylhydrazine; (tert-Butoxycarbonyl)methylhydrazine; 1-(tert-Butoxycarbonyl)-2-methylhydrazine
EINECS	Contact for details

Quality Control

Our 1-n-Boc-2-Methylhydrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.