Description

Neu5Aca2-3Galb1-3Glcn(Neu5Aca2-6)(Fuca1-4)Acb1-3Galb1-4Glc CAS NO 127783-56-6 is a complex, branched oligosaccharide, specifically a sialylated and fucosylated hexasaccharide. This compound is of significant value as a high-purity reference standard and a critical intermediate in glycobiology research and biopharmaceutical development. It is primarily needed by researchers and manufacturers in the fields of vaccine development, therapeutic antibody production, and diagnostic assay design, where precise glycan structures are essential for studying cell-cell interactions, pathogen recognition, and immune responses.

Application

• Glycobiology Research: Used as a defined substrate or inhibitor to study glycosyltransferase and glycosidase enzyme activities, specificity, and kinetics.
• Biopharmaceutical Development: Serves as a critical reference standard for the analysis and quality control of glycosylated biotherapeutics, such as monoclonal antibodies and recombinant proteins.
• Vaccine Research: Employed in the study of carbohydrate-based antigens for conjugate vaccine development against bacterial pathogens.
• Diagnostic Reagents: Acts as a key component in the development of glycan arrays and immunoassays for detecting specific antibodies or lectins.
• Cell Signaling Studies: Utilized to investigate the role of specific glycan epitopes in cell adhesion, signaling, and recognition processes.
• Enzyme Characterization: Functions as a high-value substrate for the characterization of novel microbial or engineered carbohydrate-active enzymes.

Basic Information

Product Name	Neu5Aca2-3Galb1-3Glcn(Neu5Aca2-6)(Fuca1-4)Acb1-3Galb1-4Glc
CAS No.	127783-56-6
Molecular Formula	C58H95N3O44
Molecular Weight	~1526.36 g/mol
Synonyms	Hexasaccharide, Sialyl Lewis x hexasaccharide (sLex); Neu5Acα2-3Galβ1-3[Neu5Acα2-6]GlcNAcβ1-3Galβ1-4Glc (Fucα1-4); Sialyl-dimeric-Lewis X; 3'-Sialyl-6'-sialyl-Lewis x; Branched sialyl Lewis X hexasaccharide; VIM-2 antigen hexasaccharide; CD15s hexasaccharide
EINECS	Contact for details

Quality Control

Our high-purity carbohydrate standards undergo rigorous analytical testing to ensure identity, purity, and batch-to-batch consistency, meeting the exacting requirements of research and development. Each batch is characterized by advanced techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.