Description

2-((1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Carbonyl)Benzoic Acid is a specialized aromatic carboxylic acid derivative featuring a trifluoromethylphenyl group, which imparts unique physicochemical properties critical for advanced synthesis. This compound serves as a high-value pharmaceutical intermediate and a versatile building block in organic chemistry, enabling the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated organic electronic materials for displays and lighting applications.
• Polymer Modification: Serves as a monomer or functionalizing agent to introduce aromatic carboxylic acid groups into polymer chains, altering material properties.
• Organic Synthesis & Catalysis: Valuable reagent in academic and industrial research for constructing complex molecules, often used in coupling reactions and as a ligand precursor.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and solubility profiles.

Basic Information

Product Name	2-((1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Carbonyl)Benzoic Acid
CAS No.	127733-45-3
Molecular Formula	C₁₇H₁₃F₃O₄
Molecular Weight	338.28 g/mol
Synonyms	2-({1-[2-(Trifluoromethyl)phenyl]ethoxy}carbonyl)benzoic acid; Benzoic acid, 2-[[1-[2-(trifluoromethyl)phenyl]ethoxy]carbonyl]-; α-Methyl-2-(trifluoromethyl)benzyl 2-carboxybenzoate; 2-Carboxy-α-methyl-2'-(trifluoromethyl)benzhydryl alcohol benzoate; 2-((1-(2-(Trifluoromethyl)phenyl)ethoxy)carbonyl)benzoic acid; [1-(2-Trifluoromethyl-phenyl)-ethoxy]-phthalic acid monomethyl ester (related structure); TFMPE Benzoic Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-((1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Carbonyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.