Description

3-Chloro-7,8-Dihydroquinolin-5(6H)-One is a versatile heterocyclic building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its unique fused ring structure, featuring a chlorinated quinoline core, makes it a critical precursor for the development of complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Research: Used in the development and synthesis of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a precursor for the synthesis of specialized organic ligands and complexing agents used in catalysis and advanced materials.
• Academic & R&D Laboratories: Employed in methodological studies and as a starting material for synthesizing libraries of compounds in medicinal chemistry programs.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	3-Chloro-7,8-Dihydroquinolin-5(6H)-One
CAS No.	127724-75-8
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydroquinolin-5-one; 3-Chloro-7,8-dihydro-5(6H)-quinolinone; 5(6H)-Quinolinone, 3-chloro-7,8-dihydro-; 3-Chloro-5-oxo-5,6,7,8-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 3-Chloro-7,8-Dihydroquinolin-5(6H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.