Description

Bastadin 10 is a brominated tyrosine-derived alkaloid, a member of the bastadin family of marine natural products. This compound is of significant interest in biochemical and pharmacological research due to its potent and selective activity as an inhibitor of the IP3 receptor-mediated Ca2+ release channel. Researchers and developers in the pharmaceutical and life science sectors utilize Bastadin 10 CAS NO 127687-08-5 as a critical tool compound for studying calcium signaling pathways and related cellular processes.

Application

• Biochemical Research: Used as a selective modulator of inositol 1,4,5-trisphosphate (IP3) receptor function in calcium signaling studies.
• Pharmacological Profiling: Serves as a reference standard and tool compound for investigating novel therapeutics targeting intracellular calcium regulation.
• Cell Biology Studies: Applied in research exploring the role of calcium ions in apoptosis, muscle contraction, and neurotransmitter release.
• Marine Natural Product Research: Acts as a representative compound for studying the structure-activity relationships of brominated tyrosine derivatives.
• High-Throughput Screening (HTS): Utilized in assay development and validation for drug discovery campaigns focused on calcium channel targets.
• Reference Standard: Employed for the qualitative and quantitative analysis of bastadin compounds in analytical laboratories.

Basic Information

Item	Detail
Product Name	Bastadin 10
CAS No.	127687-08-5
Molecular Formula	C34H28Br4N4O8
Molecular Weight	933.13 g/mol
Synonyms	Bastadin 10; 127687-08-5; UNII-2K8L8QJ8QN; 2K8L8QJ8QN; SCHEMBL218330; DTXSID701310183; BCP31093; Bastadin-10; (3S,10S,17S,24S)-3,10,17,24-Tetrakis(3-bromo-4-hydroxyphenyl)-1,8,15,22-tetraazatricyclo[20.4.0.09,14]hexacosa-9(14),11,25,27-tetraene-2,7,16,21-tetrone
EINECS	Contact for details

Quality Control

Our Bastadin 10 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and analytical data is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.