Description

Retinoic Acid,2-(4-Methoxyphenyl)-2-Oxoethyl Ester, 13-cis- is a specialized synthetic retinoid derivative, a high-value intermediate in advanced pharmaceutical synthesis. This compound is critical for research and development in dermatology and oncology, where precise molecular structure is paramount for biological activity. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing novel retinoid-based therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel retinoid receptor agonists and antagonists for therapeutic development.
• Dermatological Research: Used in preclinical studies for developing new treatments targeting skin conditions, including acne, psoriasis, and photoaging.
• Oncology Research: Investigated for its potential role in differentiation therapy and as a chemopreventive agent in cancer research programs.
• Biochemical Tool Compound: Serves as a ligand for studying retinoid receptor (RAR/RXR) signaling pathways and gene expression regulation.
• Cosmeceutical Actives Development: Explored in the formulation of advanced, stabilized retinoid derivatives for high-performance skincare applications.
• Organic Synthesis Reference Standard: Used as a pure reference material for analytical method development and quality control in fine chemical production.

Basic Information

Item	Details
Product Name	Retinoic Acid,2-(4-Methoxyphenyl)-2-Oxoethyl Ester, 13-cis-
CAS No.	127471-94-7
Molecular Formula	C22H24O4
Molecular Weight	352.43 g/mol
Synonyms	13-cis-Retinoic Acid 2-(4-Methoxyphenyl)-2-oxoethyl Ester; 2-(4-Methoxyphenyl)-2-oxoethyl 13-cis-retinoate; (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid 2-(4-methoxyphenyl)-2-oxoethyl ester; 13-cis Tretinoin 4-Methoxyphenacyl Ester; 4-Methoxyphenacyl 13-cis-Retinoate; Retinoid Derivative 127471-94-7
EINECS	Contact for details

Quality Control

Our Retinoic Acid,2-(4-Methoxyphenyl)-2-Oxoethyl Ester, 13-cis- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. This material is strictly light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.