Description

3-(2-(2-Aminoethoxy)Ethoxy)Propanoic Acid HCl is a high-purity, functionalized organic building block featuring a terminal amine group protected as a hydrochloride salt and a carboxylic acid terminus. This bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by researchers and process chemists in the life sciences, polymer, and specialty chemical industries for constructing targeted drug delivery systems, functional polymers, and novel linker molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in oncology and targeted therapies.
• Bioconjugation & Linker Chemistry: Used to create cleavable or stable linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for producing specialty polymers with amine and carboxyl functionalities.
• Peptide Mimetics & Prodrug Synthesis: Employed in the design and synthesis of peptide analogs and prodrug constructs to enhance bioavailability.
• Surface Functionalization: Used to modify surfaces of nanoparticles, resins, or other materials to introduce specific chemical reactivity.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and molecular architectures.

Basic Information

Item	Detail
Product Name	3-(2-(2-Aminoethoxy)Ethoxy)Propanoic Acid HCl
CAS No.	127457-79-8
Molecular Formula	C7H16ClNO4
Molecular Weight	213.66 g/mol
Synonyms	3-[2-(2-Aminoethoxy)ethoxy]propanoic acid hydrochloride; 2-[2-(2-Carboxyethoxy)ethoxy]ethylamine hydrochloride; Amino-PEG2-acid HCl; H2N-PEG2-CH2CH2COOH·HCl; 3,6-Dioxa-8-azanonanoic acid, 9-amino-, hydrochloride; 8-Amino-3,6-dioxanonanoic acid hydrochloride; PEG2-Amine-Acid HCl; AEEA-Acid HCl
EINECS	Contact for details

Quality Control

Our 3-(2-(2-Aminoethoxy)Ethoxy)Propanoic Acid HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for assay determination, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.