Description

6-Chloro-1,8-Naphthyridin-2-One is a high-purity, versatile naphthyridinone derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique fused heterocyclic structure, which provides a privileged scaffold for developing novel compounds with targeted biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and functional materials.

Application

6-Chloro-1,8-Naphthyridin-2-One is a key synthetic intermediate with applications across several high-value research and development sectors.

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors, antimicrobial agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or tag in biochemical research to study enzyme interactions and cellular processes.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-1,8-Naphthyridin-2-One
CAS No.	127446-42-8
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	6-Chloro-1,8-naphthyridin-2(1H)-one; 2(1H)-Naphthyridinone, 6-chloro-1,8-; 6-Chloro-1,8-dihydro-2H-1,8-naphthyridin-2-one; 6-Chloro-2-hydroxy-1,8-naphthyridine; 6-Chloro-1,8-naphthyridin-2-ol
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,8-Naphthyridin-2-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.