Description

n-Boc-1,3-Diaminopropane Hydrochloride is a protected diamine derivative widely used as a key building block in organic synthesis. This compound is essential for introducing a primary amine functionality with orthogonal protection, enabling complex multi-step reactions. It is particularly valuable for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing active pharmaceutical ingredients (APIs), peptide mimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors and antiviral agents.
• Peptide Chemistry: Used to incorporate a diaminoalkyl spacer or linker into peptide chains and peptidomimetics.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides a base-labile protecting group for amines, facilitating selective deprotection in complex molecular architectures.
• Cross-linking Agent: Serves as a bifunctional linker for the conjugation of biomolecules or the creation of polymer networks.
• Ligand Synthesis: A starting material for preparing chelating ligands used in catalysis and metal coordination chemistry.
• Bioconjugation: Enables the attachment of probes, dyes, or other functional groups to proteins and other biological molecules.

Basic Information

Item	Details
Product Name	n-Boc-1,3-Diaminopropane Hydrochloride
CAS No.	127346-48-9
Molecular Formula	C8H19ClN2O2
Molecular Weight	210.70 g/mol
Synonyms	1,3-Diaminopropane, N-Boc derivative hydrochloride; 3-[(tert-Butoxycarbonyl)amino]propylamine hydrochloride; N-Boc-1,3-propanediamine hydrochloride; N-(3-Aminopropyl)carbamic acid tert-butyl ester hydrochloride; tert-Butyl (3-aminopropyl)carbamate hydrochloride; Boc-1,3-diaminopropane HCl; Boc-DAP hydrochloride
EINECS	Contact for details

Quality Control

Our n-Boc-1,3-Diaminopropane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.