Description

4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Ethyl Ester is a high-purity, versatile quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which provides a key scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of quinolone-based drug candidates, including potential antibiotics and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the bioactive quinoline core.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, dyes, and fluorescent markers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Ethyl Ester
CAS No.	127286-04-8
Molecular Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22 g/mol
Synonyms	Ethyl 6-Quinolinecarboxylate, 1,4-Dihydro-4-oxo-; Ethyl 4-Oxo-1,4-dihydroquinoline-6-carboxylate; 6-(Ethoxycarbonyl)-4-hydroxyquinoline; 4-Hydroxyquinoline-6-carboxylic Acid Ethyl Ester; 1,4-Dihydro-4-oxoquinoline-6-carboxylic Acid Ethyl Ester; Quinoline-6-carboxylic Acid, 1,4-Dihydro-4-oxo-, Ethyl Ester; AKS-968; ZINC000003869756
EINECS	Contact for details

Quality Control

Our 4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.