Description

4-Nitroisoindoline is a versatile nitro-substituted isoindoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique bicyclic structure and nitro functionality, which are pivotal for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical synthesis, agrochemical discovery, and the development of specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its nitro-aromatic properties.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in electronic display technologies.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or functionalizing agent for creating high-performance polymers with specific thermal or optical properties.
• Dye and Pigment Research: Utilized as an intermediate in the development of specialized nitro-based dyes and colorants.

Basic Information

Item	Detail
Product Name	4-Nitroisoindoline
CAS No.	127168-86-9
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	4-Nitro-2,3-dihydro-1H-isoindole; 1H-Isoindole, 2,3-dihydro-4-nitro-; Isoindoline, 4-nitro-; 4-Nitroisoindoline; 4-Nitro-1H-isoindoline
EINECS	Contact for details

Quality Control

Our 4-Nitroisoindoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.