Description

4-Bromo-2-Tosylisoindoline is a high-purity, functionalized isoindoline derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and specialty materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific biological activity.
• Material Science Precursor: Employed in the creation of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.
• Custom Synthesis Building Block: Provides a brominated and tosylated handle for further functionalization via cross-coupling and substitution reactions.

Basic Information

Product Name	4-Bromo-2-Tosylisoindoline
CAS No.	127168-83-6
Molecular Formula	C15H14BrNO2S
Molecular Weight	352.25 g/mol
Synonyms	4-Bromo-2-[(4-methylphenyl)sulfonyl]-2,3-dihydro-1H-isoindole; 4-Bromo-2-(p-tolylsulfonyl)isoindoline; 2,3-Dihydro-4-bromo-2-[(4-methylphenyl)sulfonyl]-1H-isoindole; 4-Bromo-2-(4-methylbenzenesulfonyl)isoindoline; 4-Bromo-2-tosyl-2,3-dihydro-1H-isoindole; 4-Bromo-2-(p-toluenesulfonyl)isoindoline; 127168-83-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Tosylisoindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure the specified 97% minimum purity and identity are met. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.