Description

(R)-(+)-8-Methoxy-2-Aminotetralin CAS NO 127165-18-8 is a chiral, non-racemic aminotetralin derivative that serves as a critical building block in advanced organic synthesis. Its enantiopure nature is essential for the development of biologically active compounds, particularly in the pharmaceutical sector where stereochemistry dictates efficacy and safety. This high-purity intermediate is primarily sought by research institutions and fine chemical manufacturers engaged in the development of central nervous system (CNS) agents, receptor ligands, and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential dopamine receptor agonists and other CNS-targeting drug candidates.
• Asymmetric Synthesis: Employed as a versatile chiral scaffold or resolving agent in the preparation of enantiomerically pure compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the discovery of novel bioactive molecules.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Neuroscience Research: Utilized in biochemical assays and studies related to neurotransmitter systems and receptor binding.

Basic Information

Product Name	(R)-(+)-8-Methoxy-2-Aminotetralin
CAS No.	127165-18-8
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(R)-8-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine; (R)-8-Methoxy-2-aminotetralin; (R)-(+)-8-Methoxy-2-Tetralylamine; (2R)-8-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine; (R)-MAT; (R)-(+)-8-MAT
EINECS	Contact for details

Quality Control

Every batch of (R)-(+)-8-Methoxy-2-Aminotetralin is produced under strict quality management protocols. We provide comprehensive analytical documentation to ensure the material meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available for each lot, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.