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[(2R,3S)-2-(2,4-Difluoro-Phenyl)-3-Methyl-Oxiranyl]-Methanol CAS NO 126918-27-2
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CAS No.:126918-27-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
[(2R,3S)-2-(2,4-Difluoro-Phenyl)-3-Methyl-Oxiranyl]-Methanol is a high-value chiral epoxide building block, essential for the synthesis of complex bioactive molecules. Its defined stereochemistry and functional groups make it a critical intermediate for creating enantiomerically pure compounds with targeted biological activity. This compound is primarily needed by pharmaceutical R&D and manufacturing sectors for the development of new active pharmaceutical ingredients (APIs), particularly in antifungal and other therapeutic areas.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel antifungal agents and other therapeutic compounds.
- Agrochemical Research: Used in the development of advanced, stereospecific pesticides and herbicides.
- Asymmetric Synthesis: Serves as a versatile starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
- Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high enantiomeric purity.
- Academic & Industrial R&D: A valuable tool for medicinal chemistry research and process development in organic synthesis.
Basic Information
| Product Name | [(2R,3S)-2-(2,4-Difluoro-Phenyl)-3-Methyl-Oxiranyl]-Methanol |
| CAS No. | 126918-27-2 |
| Molecular Formula | C10H10F2O2 |
| Molecular Weight | 200.18 g/mol |
| Synonyms | (2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiranemethanol; (2R,3S)-2-(2,4-Difluorophenyl)-3-methylglycidol; (2R,3S)-Epoxy Alcohol Intermediate; (2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxirane-2-methanol; (2R,3S)-Glycidol Derivative; (2R,3S)-DFP-Methyl Oxirane Methanol; Chiral Difluorophenyl Epoxide Alcohol |
| EINECS | Contact for details |
Quality Control
Our [(2R,3S)-2-(2,4-Difluoro-Phenyl)-3-Methyl-Oxiranyl]-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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