Description

Boc-L-β-Homotyrosine(Obzl) CAS NO 126825-16-9 is a protected, non-proteinogenic amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the research and development of novel peptides and peptidomimetics, offering precise control over molecular structure and function. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating bioactive molecules, drug candidates, and specialized biochemical tools.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to incorporate the homotyrosine side chain into peptidomimetic structures, which are designed to mimic natural peptides with enhanced stability and bioavailability.
• Bioconjugation & Probe Development: Serves as a modified amino acid for creating labeled peptides, fluorescent probes, or affinity tags used in biochemical assays and diagnostic research.
• Academic & Industrial R&D: Employed in medicinal chemistry and chemical biology research to explore structure-activity relationships (SAR) and develop new therapeutic entities.
• Custom Peptide Synthesis: A valuable building block for contract research organizations (CROs) and CDMOs producing custom, non-standard peptides for clients.

Basic Information

Product Name	Boc-L-β-Homotyrosine(Obzl)
CAS No.	126825-16-9
Molecular Formula	C22H27NO6
Molecular Weight	401.46 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-4-(benzyloxy)-4-phenylbutanoic Acid; Boc-β-homo-Tyr(OBzl)-OH; N-(tert-Butoxycarbonyl)-3-(4-(benzyloxy)phenyl)-L-homoalanine; Boc-L-β-Homotyrosine benzyl ether; Boc-β-Htyr(OBzl)-OH; N-Boc-β-homo-O-benzyl-L-tyrosine; tert-Butyl (1S)-1-carboxy-3-[4-(phenylmethoxy)phenyl]propylcarbamate
EINECS	Contact for details

Quality Control

Our Boc-L-β-Homotyrosine(Obzl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity	≥99.0%
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.