Description

2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Phenyl-Propionic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in solid-phase peptide synthesis (SPPS). This compound matters for its role in enabling the precise and efficient construction of complex peptides and peptidomimetics, ensuring high coupling yields and purity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools. The product is supplied under strict quality control to guarantee batch-to-batch consistency for sensitive applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated, stepwise assembly of peptide chains.
• Pharmaceutical Research & Development: For the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to introduce specific phenylalanine-derived moieties into proteins, antibodies, or other biomolecules.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening of bioactive compounds.
• Biochemical Tool Development: Synthesis of substrates, inhibitors, or probes for enzymatic studies and diagnostic assays.
• Academic Research: Fundamental studies in organic chemistry, peptide chemistry, and medicinal chemistry.

Basic Information

Product Name	2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Phenyl-Propionic Acid
CAS No.	126727-04-6
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-Phenylalanine-OH; Fmoc-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine; N-α-Fmoc-L-phenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-phenylpropanoic acid; Fmoc-L-Phe; Fmoc-Phenylalanine; N-Fmoc-L-phenylalanine
EINECS	Contact for details

Quality Control

Our 2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Phenyl-Propionic Acid is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for peptide synthesis. Each batch is characterized by HPLC, NMR, and optical rotation analysis to confirm identity, purity, and enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.