Description

(1S,2R)-(-)-cis-1-Amino-2-Indanol CAS NO 126456-43-7 is a high-value, enantiomerically pure chiral building block and ligand. This compound is critically important for its role in asymmetric synthesis, where it acts as a highly effective catalyst or auxiliary to induce stereoselectivity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of chiral active pharmaceutical ingredients (APIs) and other optically active compounds.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation and transfer hydrogenation reactions.
• As a key building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• As a resolving agent for the separation of enantiomers in racemic mixtures.
• In the preparation of chiral auxiliaries for stereocontrolled organic synthesis.
• For research and development of novel catalytic systems in academic and industrial laboratories.
• In the synthesis of agrochemicals and other specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(1S,2R)-(-)-cis-1-Amino-2-Indanol
CAS No.	126456-43-7
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(1S,2R)-1-Amino-2,3-dihydro-1H-inden-2-ol; (1S,2R)-1-Aminoindan-2-ol; (-)-cis-1-Amino-2-indanol; (1S,2R)-(-)-cis-1-Amino-2-indanol; cis-(1S,2R)-1-Amino-2-indanol; (1S,2R)-2-Amino-1-indanol; Aminoindanol; Chiral Aminoindanol; Chiral Indanol Derivative
EINECS	Contact for details

Quality Control

Our (1S,2R)-(-)-cis-1-Amino-2-Indanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	92 - 96 °C
Specific Rotation	-35° to -39° (c=1 in MeOH)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.